| Product Name |
mtCheck™ NIR Mitochondrial Membrane Potential Assay Kit (For Microplates) (KITA1013) |
| Description |
This kit is a fluorescent assay used to detect cell apoptosis by monitoring the loss of mitochondiral membrane potential with flow cytometry. The collapse of the mitochondrial membrane potential occurs simultaneously with the opening of the mitochondrial permeability transition pore, leading to the release of cytochrome C into the cytoplasm, which in turn triggers other downstream events in the apoptotic cascade response. In normal cells, as the NIR dye accumulates in the mitochondria, the intensity of red fluorescence increases. In apoptotic cells, NIR fluorescence intensity decreases after MMP collapse. |
| Catalog Number |
KITA1013 |
| Suitable Sample |
Adherent cells, Non-adherent cells |
| Storage Instruction |
Store at -20°C and avoid from light |
| Usage Statement |
Our products are intended for research use only and are not to be used for other purposes, including but are not limited to in vitro diagnostic uses, ex vivo or in vivo therapeutic uses. |
| Detection Method |
Fluorescence microplate platform |
