Analysis of Substances Related to NAD Metabolism
Creative Biogene can efficiently and accurately detect the changes of small molecules related to DAN and NAD metabolism by using the basic technique of GC/MS, ACQUITY UPLC/TripleQuad5500. A variety of one-stop testing services are only designed to meet the different needs of customers around the world.
Nicotinamide adenine dinucleotide (NAD+), also known as coenzyme I, is an essential coenzyme in the redox process. In redox reactions, NADH acts as the donor of hydrogen and electrons, and NAD+, as the acceptor of hydrogen and electrons, participates in physiological processes such as respiration, photosynthesis, cellular metabolism, and energy synthesis. As coenzymes of many redox reactions in organisms, they participate in life activities and transform each other.
Figure 1. An overview of NAD metabolism. (Chong K. S., et al., 2020)
Creative Biogene has established a NAD metabolism-related small molecule detection platform based on GC/MS and ACQUITY UPLC/TripleQuad5500 (Waters/AB Sciex) to analyze NAD metabolism-related small molecules qualitatively and quantitatively. 95% of the substances involved are quantified using isotope standard.
General Strategy
NAD metabolism-related small molecules mainly include an oxidized NAD+, reduced form of NADH, oxidized NADP+, reduced form of NADPH, NMN, NAM, NaR, and ATP. Please contact us if your substance is not listed here. We are committed to providing professional and accurate testing and analysis services for all customers.
At the end of the experiment, Creative Biogene technicians will provide you with a detailed technical report as soon as possible, including experimental steps, relevant MS parameters, quantitative or quantitative information of the identified substances, MS images, and detailed real raw data.
Creative Biogene always provides you with customized services for mitochondrial research, and our one-stop research and analysis platform can meet all your research needs.
Our Advantages
- Rich experience in the analysis of substances related to NAD metabolism
- Outstanding research team
- Unique integrated service for mitochondrial research
- Reliable data and results
- Rapid turnaround and cost-effective
Creative Biogene has the most professional team to serve customers around the world. If you have any questions about the content of this service, please feel free to contact us. We look forward to your contact.
Reference
- Chong K. S., et al. " Re-equilibration of imbalanced NAD metabolism ameliorates the impact of telomere dysfunction. " The EMBO Journal, 2020, 39: e103420.
For Research Use Only. Not For Clinical Use Or Individual Users.
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